Pharmacology 1 - Unit 2


General Pharmacology

  • Pharmacodynamics- Principles and mechanisms of drug action. Receptor theories and classification of receptors, regulation of receptors. drug receptors interactions signal transduction mechanisms, G-protein-coupled receptors, ion channel receptor, transmembrane enzyme linked receptors, transmembrane JAK-STAT binding receptor and receptors that regulate transcription factors, dose response relationship, therapeutic index, combined effects of drugs and factors modifying drug action.
  • Adverse drug reactions.
  • Drug interactions (pharmacokinetic and pharmacodynamic)
  • Drug discovery and clinical evaluation of new drugs -Drug discovery phase, preclinical evaluation phase, clinical trial phase, phases of clinical trials and pharmacovigilance.

Unit 2, Pharmacology 1, B Pharmacy 4th Sem, Carewell Pharma
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