Unit 1

Medicinal Chemistry 2

Medicinal Chemistry 2 - Antihistaminic agents | Anti-neoplastic agents | Miscellaneous |

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Syllabus :- Antihistaminic agents: Histamine, receptors and their distribution in the humanbody H1–antagonists Diphenhydramine hydrochloride*, Dimenhydrinate, Doxylamines cuccinate, Clemastine fumarate, Diphenylphyraline hydrochloride, Tripelenamine hydrochloride, Chlorcyclizine hydrochloride, Meclizine hydrochloride, Buclizine hydrochloride, Chlorpheniramine maleate, Triprolidine hydrochloride*, Phenidamine tartarate, Promethazine hydrochloride*, Trimeprazine tartrate, Cyproheptadine hydrochloride, Azatidine maleate, Astemizole, Loratadine, Cetirizine, Levocetrazine Cromolyn sodium H2-antagonists: Cimetidine*, Famotidine, Ranitidin. Gastric Proton pump inhibitors: Omeprazole, Lansoprazole, Rabeprazole, Pantoprazole Anti-neoplastic agents: Alkylating agents: Meclorethamine*, Cyclophosphamide, Melphalan, Chlorambucil, Busulfan, Thiotepa Antimetabolites: Mercaptopurine*, Thioguanine, Fluorouracil, Floxuridine, Cytarabine, Methotrexate*, Azathioprine Antibiotics: Dactinomycin, Daunorubicin, Doxorubicin, Bleomycin Plant products: Etoposide, Vinblastin sulphate, Vincristin sulphate Miscellaneous: Cisplatin, Mitotane. DEFINE Antihistaminic agents: Antihistamines are medications that help with allergies, and also with stomach problems, cold, anxiety and more. Antihistamines are a class of drugs commonly used to treat symptoms of allergies. These drugs help treat conditions caused by too much histamine, a chemical created by your body's immune system. Anti-neoplastic agents: Antineoplastic agents that are well known to cause significant direct hepatotoxicity when given in moderate to high doses (particularly when used in myeloablation before hematopoietic cell transplantation) include busulfan, melphalan, cyclophosphamide, dacarbazine, cytarabine, fluorouracil, carboplatin and L- ... 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Gastric Proton pump inhibitors Gastric Proton pump inhibitors Omeprazole Gastric Proton pump inhibitors Lansoprazole Gastric Proton pump inhibitors Rabeprazole Gastric Proton pump inhibitors Pantoprazole Anti-neoplastic agents Alkylating agents Alkylating agents Meclorethamine Alkylating agents Cyclophosphamide Alkylating agents Melphalan Alkylating agents Chlorambucil Alkylating agents Busulfan Alkylating agents Thiotepa Antimetabolites Antimetabolites Mercaptopurine Antimetabolites Thioguanine Antimetabolites Fluorouracil Antimetabolites Floxuridine Antimetabolites Cytarabine Antimetabolites Methotrexate Antimetabolites Azathioprine Antibiotics Antibiotics Dactinomycin Antibiotics Daunorubicin Antibiotics Doxorubicin Antibiotics Bleomycin Plant products Plant products Etoposide Plant products Vinblastin sulphate Plant products Vincristin sulphate Miscellaneous Miscellaneous Cisplatin Miscellaneous Mitotane

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