Unit 3

Medicinal Chemistry 1

Medicinal Chemistry - Cholinesterase reactivator | Cholinergic neurotransmitters | Synthetic cholinergic blocking agents |

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Syllabus :- Cholinergic neurotransmitters: Biosynthesis and catabolism of acetylcholine. Cholinergic receptors (Muscarinic & Nicotinic) and their distribution. Parasympathomimetic agents: SAR of Parasympathomimetic agents Direct acting agents: Acetylcholine, Carbachol*, Bethanechol, Methacholine, Pilocarpine. Indirect acting/ Cholinesterase inhibitors (Reversible & Irreversible): Physostigmine, Neostigmine*, Pyridostigmine, Edrophonium chloride, Tacrine hydrochloride, Ambenonium chloride, Isofluorphate, Echothiophate iodide, Parathione, Malathion. Cholinesterase reactivator: Pralidoxime chloride. Cholinergic Blocking agents: SAR of cholinolytic agents Synthetic cholinergic blocking agents: Atropine sulphate, Hyoscyamine sulphate, Scopolamine hydrobromide, Homatropine hydrobromide, Ipratropium bromide*. Synthetic cholinergic blocking agents: Tropicamide, Cyclopentolate hydrochloride, Clidinium bromide, Dicyclomine hydrochloride*, Glycopyrrolate, Methantheline bromide, Propantheline bromide, Benztropine mesylate, Orphenadrine citrate, Biperidine hydrochloride, Procyclidine hydrochloride*, Tridihexethyl chloride, Isopropamide iodide, Ethopropazine hydrochloride. DEFINATION Introduction to Medicinal Chemistry: Medicinal chemistry is discipline at the intersection of chemistry, especially synthetic organic chemistry, and pharmacology and various other biological specialties, where they are involved with design, chemical synthesis and development for market of pharmaceutical agents, or bio-active molecules. Cholinergic neurotransmitters: Indications. Cholinergic medications are a category of pharmaceutical agents that act upon the neurotransmitter acetylcholine, the primary neurotransmitter within the parasympathetic nervous system (PNS). There are two broad categories of cholinergic drugs: direct-acting and indirect-acting. Synthetic cholinergic blocking agents: Cholinergic blocking drugs are a group of drugs that block the action of acetylcholine (ACh), a neurotransmitter, in synapses of the cholinergic nervous system. They block acetylcholine from binding to cholinergic receptors, namely the nicotinic and muscarinic receptors. Central Nervous System (CNS): Restlessness, ... Other smooth muscle: Relaxation of bronchial ... Eye: Pupil dilation (mydriasis) and unresponsive ... Exocrine glands: Inhibition of secretions in sali... UNIT 3rd Medicinal Chemistry unit 3 pdf Medicinal Chemistry pdf Medicinal Chemistry definition Medicinal Chemistry unit 3 notes Medicinal Chemistry unit 3 pdf download Medicinal Chemistry unit 3 pdf Medicinal Chemistry unit 3 notes pdf Medicinal Chemistry unit 3 notes Medicinal Chemistry unit 3 notes download Medicinal Chemistry syllabus Medicinal Chemistry question paper Medicinal Chemistry 4th semester practical book pdf Medicinal Chemistry 4th semester book pdf Medicinal Chemistry 4th semester Medicinal Chemistry 4th semester important questions Medicinal Chemistry unit 3 pdf Medicinal Chemistry pdf Medicinal Chemistry definition Medicinal Chemistry unit 3 notes Medicinal Chemistry unit 3 pdf download Medicinal Chemistry unit 3 pdf Medicinal Chemistry unit 3 notes pdf Medicinal Chemistry unit 3 notes Medicinal Chemistry unit 3 notes download Medicinal Chemistry syllabus Medicinal Chemistry question paper Medicinal Chemistry 4th semester practical book pdf Medicinal Chemistry 4th semester book pdf Medicinal Chemistry 4th semester Medicinal Chemistry 4th semester important questions Cholinergic neurotransmitters: Biosynthesis and catabolism of acetylcholine Cholinergic receptors (Muscarinic & Nicotinic) and their distribution. Parasympathomimetic agents Parasympathomimetic agents SAR of Parasympathomimetic agents Direct acting agents Direct acting agents Acetylcholine Direct acting agents Carbachol Direct acting agents Bethanechol Direct acting agents Methacholine Direct acting agents Pilocarpine. Indirect acting/ Cholinesterase inhibitors (Reversible & Irreversible): Physostigmine Neostigmine Pyridostigmine Edrophonium chloride Tacrine hydrochloride Ambenonium chloride Isofluorphate Echothiophate iodide Parathione Malathion Cholinesterase reactivator Cholinesterase reactivator Pralidoxime chloride. Cholinergic Blocking agents Cholinergic Blocking agents SAR of cholinolytic agents Synthetic cholinergic blocking agents Synthetic cholinergic blocking agents Atropine sulphate Synthetic cholinergic blocking agents Hyoscyamine sulphate Synthetic cholinergic blocking agents Scopolamine hydrobromide Synthetic cholinergic blocking agents Homatropine hydrobromide Synthetic cholinergic blocking agents Ipratropium bromide Synthetic cholinergic blocking agents Tropicamide Cyclopentolate hydrochloride Clidinium bromide Dicyclomine hydrochloride Glycopyrrolate Methantheline bromide Propantheline bromide Benztropine mesylate Orphenadrine citrate Biperidine hydrochloride Procyclidine hydrochloride Tridihexethyl chloride Isopropamide iodide Ethopropazine hydrochloride cholinergic neurotransmitters cholinergic neurotransmitters medicinal chemistry ppt cholinergic neurotransmitter ppt cholinergic neurotransmitters released neurotransmitters cholinergic system cholinergic receptors bind neurotransmitters released from examples of cholinergic neurotransmitters synthetic cholinergic blocking agents slideshare synthetic cholinergic blocking agents synthetic cholinergic blocking agents definition synthetic cholinergic blocking agents pdf

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